Position: AI Agents in Scientific Teams Should Be Studied as Human-Agent Systems

Large language model-based agents are increasingly deployed as collaborators in scientific discovery yet most current work focuses on the autonomous capabilities of "AI Scientists". We argue that this overlooks the social aspects of scientific teamwork, and that studying AI Scientists as human-agent systems (HAS)—where the unit of analysis is the human-agent pair—is both underexplored and undervalued. We establish these points through literature and empirical analysis, and highlight recent incidences and studies which show that deploying agents in science without accounting for human-agent dynamics introduces near-term risks, including reduced diversity of scientific inquiry. Through analysis of real-world case studies, we show that scientists and agents can augment each other's capabilities. We call for new research that adopts the HAS lens to develop mathematical frameworks for understanding and fostering human-AI synergy in scientific discovery.